Įpidemics and pandemics with at least 1 million deathsĬocoliztli, caused by an unidentified pathogenįurther information: List of causes of death by rate For the historical records of major changes in the world population, see world population. If the death toll averages of two or more epidemics are equal, then the smaller the range, the higher the rank. For a given epidemic, the average of its estimated death toll range is used for ranking. Major epidemics and pandemics By death toll Infectious diseases with high prevalence are listed separately (sometimes in addition to their epidemics), such as malaria, which may have killed 50–60 billion people throughout history, or about half of all humans that have ever lived. Due to the long time spans, the first plague pandemic (6th century – 8th century) and the second plague pandemic (14th century – early 19th century) are shown by individual outbreaks, such as the Plague of Justinian (first pandemic) and the Black Death (second pandemic). An epidemic is the rapid spread of disease to a large number of people in a given population within a short period of time in meningococcal infections, an attack rate in excess of 15 cases per 100,000 people for two consecutive weeks is considered an epidemic. Widespread non-communicable diseases such as cardiovascular disease and cancer are not included. This is a list of the largest known epidemics and pandemics caused by an infectious disease. A plague epidemic raged in Augsburg, Bavaria, between 16. Panels of this kind were placed on the walls of houses to warn against the plague. 17th-century German "plague panel" depicting the triumph of death.
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